Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres
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چکیده
منابع مشابه
Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres
Formation of neurospheres (NS) in cultures of glioblastomas (GBMs), with self-renewal, clonogenic capacities, and tumorigenicity following transplantation into immunodeficient mice, may denounce the existence of brain tumor stem cells (BTSCs) in vivo. In sixteen cell lines from resected primary glioblastomas, NS showed the same genetic alterations as primary tumors and the expression of stemnes...
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ژورنال
عنوان ژورنال: Journal of Oncology
سال: 2011
ISSN: 1687-8450,1687-8469
DOI: 10.1155/2011/314962